South America cruises from $410
Zero booking fees on every South America sailing, plus perks like onboard credit, free excursions, and gift cards on select departures.
Best South America Cruise Prices by Line
South America pairs big-city energy with wild coastline, from Rio’s beaches to Patagonian channels and the Amazon itself. Compare real current prices from the lines sailing the continent, updated every day.
Celebrity
Upscale ships, modern design
From $1,530
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MSC Cruises
Modern ships, European-style service
From $410
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Silversea
All-inclusive ultra-luxury voyages
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Costa
Italian-style cruising
From $432
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Avalon Waterways
Panoramic river cruising
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Uniworld
Boutique luxury river cruises
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Seabourn
Intimate ultra-luxury ships
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Viking Expeditions
Polar expedition voyages in comfort
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Best Time to Sail South America
The main South America season runs through the austral summer, roughly November to March, when Brazil’s coast and the far south are at their best.
Popular South America Departure Ports
Real departure ports from our current inventory, with the most South America sailings today. Pick your closest port to see what’s sailing.

The gateway city for Galapagos expeditions

South America and Antarctica voyages

Where Galapagos sailings embark

South America sailings beneath Sugarloaf

The cruise capital of the world

Sail straight from Manhattan
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South America Itinerary Types
Amazon river runs, Brazilian coastal hops, Galapagos wildlife or a grand voyage around the continent. Pick your South America.
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Frequently Asked Questions
The core season is the austral summer, roughly November through March, when Brazil’s beaches and the far south enjoy their warmest weather. Amazon and Galapagos expeditions operate across a wider window.
Buenos Aires, Rio de Janeiro and Santos host many of the coastal sailings, while Galapagos voyages are usually reached through Quito or Guayaquil in Ecuador. Some itineraries also start from North American ports as longer repositioning voyages.
Entry requirements vary by nationality and by country visited, and some countries also require specific vaccination documentation. Review the rules for every port on your itinerary well before departure.
Galapagos itineraries use small expedition ships with naturalist guides, and daily landings focus on wildlife found nowhere else on Earth. Capacity is limited by park rules, so booking early matters.
Coastal Brazil itineraries can be under a week, while Amazon, Patagonia and around-the-continent voyages commonly run from 10 nights to several weeks.